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Prion Protein-Specific Antibodies that Detect Multiple TSE Agents with High Sensitivity

This paper describes the generation, characterisation and potential applications of a panel of novel anti-prion protein monoclonal antibodies (mAbs). The mAbs were generated by immunising PRNP null mice, using a variety of regimes, with a truncated form of recombinant ovine prion protein spanning re...

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Detalles Bibliográficos
Autores principales: McCutcheon, Sandra, Langeveld, Jan P. M., Tan, Boon Chin, Gill, Andrew C., de Wolf, Christopher, Martin, Stuart, Gonzalez, Lorenzo, Alibhai, James, Blanco, A. Richard Alejo, Campbell, Lauren, Hunter, Nora, Houston, E. Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946747/
https://www.ncbi.nlm.nih.gov/pubmed/24608105
http://dx.doi.org/10.1371/journal.pone.0091143