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Optimization and comprehensive characterization of a faithful tissue culture model of the benign and malignant human prostate

Few preclinical models accurately depict normal human prostate tissue or primary prostate cancer (PCa). In vitro systems typically lack complex cellular interactions among structured prostatic epithelia and a stromal microenvironment, and genetic and molecular fidelity are concerns in both in vitro...

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Detalles Bibliográficos
Autores principales: Maund, Sophia L., Nolley, Rosalie, Peehl, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946793/
https://www.ncbi.nlm.nih.gov/pubmed/24296879
http://dx.doi.org/10.1038/labinvest.2013.141