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Optimization and comprehensive characterization of a faithful tissue culture model of the benign and malignant human prostate
Few preclinical models accurately depict normal human prostate tissue or primary prostate cancer (PCa). In vitro systems typically lack complex cellular interactions among structured prostatic epithelia and a stromal microenvironment, and genetic and molecular fidelity are concerns in both in vitro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946793/ https://www.ncbi.nlm.nih.gov/pubmed/24296879 http://dx.doi.org/10.1038/labinvest.2013.141 |