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Transformation of taxol-stabilized microtubules into inverted tubulin tubules triggered by a tubulin conformation switch
Bundles of taxol-stabilized microtubules (MTs) – hollow tubules comprised of assembled αβ-tubulin heterodimers – spontaneously assemble above a critical concentration of tetravalent spermine and are stable over long times at room temperature. Here we report that at concentrations of spermine several...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946914/ https://www.ncbi.nlm.nih.gov/pubmed/24441880 http://dx.doi.org/10.1038/nmat3858 |