Cargando…

Role of Stoichiometry in the Dimer-Stabilizing Effect of AMPA Receptor Allosteric Modulators

[Image: see text] Protein dimerization provides a mechanism for the modulation of cellular signaling events. In α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors, the rapidly desensitizing, activated state has been correlated with a weakly dimeric, glutamate-binding domain confo...

Descripción completa

Detalles Bibliográficos
Autores principales: Ptak, Christopher P., Hsieh, Ching-Lin, Weiland, Gregory A., Oswald, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947009/
https://www.ncbi.nlm.nih.gov/pubmed/24152170
http://dx.doi.org/10.1021/cb4007166