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Role of Stoichiometry in the Dimer-Stabilizing Effect of AMPA Receptor Allosteric Modulators
[Image: see text] Protein dimerization provides a mechanism for the modulation of cellular signaling events. In α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors, the rapidly desensitizing, activated state has been correlated with a weakly dimeric, glutamate-binding domain confo...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical
Society
2013
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947009/ https://www.ncbi.nlm.nih.gov/pubmed/24152170 http://dx.doi.org/10.1021/cb4007166 |