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Glycolytic fast-twitch muscle fiber restoration counters adverse age-related changes in body composition and metabolism

Aging is associated with the development of insulin resistance, increased adiposity, and accumulation of ectopic lipid deposits in tissues and organs. Starting in mid-life there is a progressive decline in lean muscle mass associated with the preferential loss of glycolytic, fast-twitch myofibers. H...

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Detalles Bibliográficos
Autores principales: Akasaki, Yuichi, Ouchi, Noriyuki, Izumiya, Yasuhiro, Bernardo, Barbara L, LeBrasseur, Nathan K, Walsh, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947044/
https://www.ncbi.nlm.nih.gov/pubmed/24033924
http://dx.doi.org/10.1111/acel.12153