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Surface L-type Ca(2+) channel expression levels are increased in aged hippocampus

Age-related increase in L-type Ca(2+) channel (LTCC) expression in hippocampal pyramidal neurons has been hypothesized to underlie the increased Ca(2+) influx and subsequent reduced intrinsic neuronal excitability of these neurons that lead to age-related cognitive deficits. Here, using specific ant...

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Detalles Bibliográficos
Autores principales: Núñez-Santana, Félix Luis, Oh, Myongsoo Matthew, Antion, Marcia Diana, Lee, Amy, Hell, Johannes Wilhelm, Disterhoft, John Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947046/
https://www.ncbi.nlm.nih.gov/pubmed/24033980
http://dx.doi.org/10.1111/acel.12157