Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic (13)C magnetic resonance spectroscopy

Despite the central role of the liver in the regulation of glucose and lipid metabolism there are currently no methods to directly assess hepatic oxidative metabolism in humans in vivo. By utilizing a novel (13)C-labeling strategy in combination with (13)C magnetic resonance spectroscopy we show tha...

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Detalles Bibliográficos
Autores principales: Befroy, Douglas E., Perry, Rachel J., Jain, Nimit, Dufour, Sylvie, Cline, Gary W., Trimmer, Jeff, Brosnan, Julia, Rothman, Douglas L., Petersen, Kitt Falk, Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947269/
https://www.ncbi.nlm.nih.gov/pubmed/24317120
http://dx.doi.org/10.1038/nm.3415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947269/
https://www.ncbi.nlm.nih.gov/pubmed/24317120
http://dx.doi.org/10.1038/nm.3415

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