Sterilization of granulomas is common in both active and latent tuberculosis despite extensive within-host variability in bacterial killing

Over 30% of the world’s population is infected with Mycobacterium tuberculosis (Mtb), yet only ~5–10% will develop clinical disease(1). Despite considerable effort, we understand little about what distinguishes individuals who progress to active tuberculosis (TB) from those who remain latent for dec...

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Detalles Bibliográficos
Autores principales: Lin, Philana Ling, Ford, Christopher B., Coleman, M. Teresa, Myers, Amy J., Gawande, Richa, Ioerger, Thomas, Sacchettini, James, Fortune, Sarah M., Flynn, JoAnne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947310/
https://www.ncbi.nlm.nih.gov/pubmed/24336248
http://dx.doi.org/10.1038/nm.3412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947310/
https://www.ncbi.nlm.nih.gov/pubmed/24336248
http://dx.doi.org/10.1038/nm.3412

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