Transcription-generated torsional stress destabilizes nucleosomes

As RNA Polymerase II (Pol II) transcribes a gene, it encounters an array of well-ordered nucleosomes. How it traverses through this array in vivo remains unresolved. One model proposes that torsional stress generated during transcription destabilizes nucleosomes ahead of Pol II. Here, we describe a...

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Detalles Bibliográficos
Autores principales: Teves, Sheila S., Henikoff, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947361/
https://www.ncbi.nlm.nih.gov/pubmed/24317489
http://dx.doi.org/10.1038/nsmb.2723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947361/
https://www.ncbi.nlm.nih.gov/pubmed/24317489
http://dx.doi.org/10.1038/nsmb.2723

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