mRNA–mRNA duplexes that auto-elicit Staufen1-mediated mRNA decay

We report a new mechanism by which human mRNAs crosstalk: an Alu element in the 3'-untranslated region (3' UTR) of one mRNA can base-pair with a partially complementary Alu element in the 3' UTR of a different mRNA thereby creating a Staufen1 (STAU1)-binding site (SBS). STAU1 binding...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Chenguang, Tang, Yalan, Maquat, Lynne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947523/
https://www.ncbi.nlm.nih.gov/pubmed/24056942
http://dx.doi.org/10.1038/nsmb.2664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947523/
https://www.ncbi.nlm.nih.gov/pubmed/24056942
http://dx.doi.org/10.1038/nsmb.2664

Ejemplares similares