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mRNA–mRNA duplexes that auto-elicit Staufen1-mediated mRNA decay

We report a new mechanism by which human mRNAs crosstalk: an Alu element in the 3'-untranslated region (3' UTR) of one mRNA can base-pair with a partially complementary Alu element in the 3' UTR of a different mRNA thereby creating a Staufen1 (STAU1)-binding site (SBS). STAU1 binding...

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Detalles Bibliográficos
Autores principales:	Gong, Chenguang, Tang, Yalan, Maquat, Lynne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947523/ https://www.ncbi.nlm.nih.gov/pubmed/24056942 http://dx.doi.org/10.1038/nsmb.2664

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