Human osteosarcoma CD49f(−)CD133(+) cells: impaired in osteogenic fate while gain of tumorigenicity

The biological relationships among self-renewal, tumorigenicity, and lineage differentiation of human osteosarcoma-initiating cells (OSIC) remain elusive, making it difficult to identify and distinguish OSIC from osteosarcoma-forming cells (OSFC) for developing OSIC-targeted therapies. Using a new i...

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Detalles Bibliográficos
Autores principales: Ying, Meidan, Liu, Gang, Shimada, Hiroyuki, Ding, Wanjing, May, William A., He, Qiaojun, Adams, Gregor B., Wu, Lingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947577/
https://www.ncbi.nlm.nih.gov/pubmed/23045288
http://dx.doi.org/10.1038/onc.2012.438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947577/
https://www.ncbi.nlm.nih.gov/pubmed/23045288
http://dx.doi.org/10.1038/onc.2012.438

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