Sphingosine Phosphate Lyase Regulates Murine Embryonic Stem Cell Proliferation and Pluripotency through an S1P(2)/STAT3 Signaling Pathway

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that activates a family of G protein coupled-receptors (GPCRs) implicated in mammalian development, angiogenesis, immunity and tissue regeneration. S1P functions as a trophic factor for many cell types, including embryonic stem cells (ESCs)....

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Detalles Bibliográficos
Autores principales: Smith, Gaelen S., Kumar, Ashok, Saba, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947625/
https://www.ncbi.nlm.nih.gov/pubmed/24619572
http://dx.doi.org/10.3390/biom3030351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947625/
https://www.ncbi.nlm.nih.gov/pubmed/24619572
http://dx.doi.org/10.3390/biom3030351

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