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GCK Gene-Body Hypomethylation Is Associated with the Risk of Coronary Heart Disease

Objectives. Glucokinase encoded by GCK is a key enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Variants of GCK gene were shown to be associated with type 2 diabetes (T2D) and coronary heart disease (CHD). The goal of this study was to investigate the contribution of GCK g...

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Detalles Bibliográficos
Autores principales: Xu, Limin, Zheng, Dawei, Wang, Lingyan, Jiang, Danjie, Liu, Haibo, Xu, Leiting, Liao, Qi, Zhang, Lina, Liu, Panpan, Shi, Xinbao, Wang, Zhaoyang, Sun, Lebo, Zhou, Qingyun, Li, Ni, Huang, Yi, Le, Yanping, Ye, Meng, Shao, Guofeng, Duan, Shiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947703/
https://www.ncbi.nlm.nih.gov/pubmed/24696842
http://dx.doi.org/10.1155/2014/151723