Nodal Promotes the Self-Renewal of Human Colon Cancer Stem Cells via an Autocrine Manner through Smad2/3 Signaling Pathway

Colorectal cancer is one of the most common and fatal tumors. However, molecular mechanisms underlying carcinogenesis of colorectal cancer remain largely undefined. Here, we explored the expression and function of Nodal in colon cancer stem cells (CCSCs). Nodal and its receptors were present in nume...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Yuehua, Guo, Ying, Hai, Yanan, Yang, Hao, Liu, Yang, Yang, Shi, Zhang, Zhenzhen, Ma, Meng, Liu, Linhong, Li, Zheng, He, Zuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947734/
https://www.ncbi.nlm.nih.gov/pubmed/24696849
http://dx.doi.org/10.1155/2014/364134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947734/
https://www.ncbi.nlm.nih.gov/pubmed/24696849
http://dx.doi.org/10.1155/2014/364134

Ejemplares similares