Cargando…

Identification of Binding Sites in Huntingtin for the Huntingtin Interacting Proteins HIP14 and HIP14L

Huntington disease is an adult onset neurodegenerative disease characterized by motor, cognitive, and psychiatric dysfunction, caused by a CAG expansion in the HTT gene. Huntingtin Interacting Protein 14 (HIP14) and Huntingtin Interacting Protein 14-like (HIP14L) are palmitoyl acyltransferases (PATs...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanders, Shaun S., Mui, Katherine K. N., Sutton, Liza M., Hayden, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947954/
https://www.ncbi.nlm.nih.gov/pubmed/24651384
http://dx.doi.org/10.1371/journal.pone.0090669