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Improved Expression of Recombinant Human Factor IX by Co-expression of GGCX, VKOR and Furin
Recombinant human FIX concentrates (rhFIX) are essential in the treatment and prevention of bleeding in the bleeding disorder haemophilia B. However, due to the complex nature of FIX production yields are low which leads to high treatment costs. Here we report the production of rhFIX with substantia...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947961/ https://www.ncbi.nlm.nih.gov/pubmed/24567122 http://dx.doi.org/10.1007/s10930-014-9550-5 |