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The interplay between iron accumulation, mitochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders

A growing set of observations points to mitochondrial dysfunction, iron accumulation, oxidative damage and chronic inflammation as common pathognomonic signs of a number of neurodegenerative diseases that includes Alzheimer’s disease, Huntington disease, amyotrophic lateral sclerosis, Friedrich’s at...

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Detalles Bibliográficos
Autores principales: Urrutia, Pamela J., Mena, Natalia P., Núñez, Marco T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948003/
https://www.ncbi.nlm.nih.gov/pubmed/24653700
http://dx.doi.org/10.3389/fphar.2014.00038