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CaMKII-dependent regulation of cardiac Na(+) homeostasis
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, Na(V)1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias. Ca(2)(+)/calmodulin-dependent protein kinas...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948048/ https://www.ncbi.nlm.nih.gov/pubmed/24653702 http://dx.doi.org/10.3389/fphar.2014.00041 |