ATM specifically mediates repair of double-strand breaks with blocked DNA ends

Ataxia telangiectasia is caused by mutations in ATM and represents a paradigm for cancer predisposition and neurodegenerative syndromes linked to deficiencies in the DNA-damage response. The role of ATM as a key regulator of signalling following DNA double-strand breaks (DSBs) has been dissected in...

Descripción completa

Detalles Bibliográficos
Autores principales: Álvarez-Quilón, Alejandro, Serrano-Benítez, Almudena, Ariel Lieberman, Jenna, Quintero, Cristina, Sánchez-Gutiérrez, Daniel, Escudero, Luis M., Cortés-Ledesma, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948078/
https://www.ncbi.nlm.nih.gov/pubmed/24572510
http://dx.doi.org/10.1038/ncomms4347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948078/
https://www.ncbi.nlm.nih.gov/pubmed/24572510
http://dx.doi.org/10.1038/ncomms4347

Ejemplares similares