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ATM specifically mediates repair of double-strand breaks with blocked DNA ends

Ataxia telangiectasia is caused by mutations in ATM and represents a paradigm for cancer predisposition and neurodegenerative syndromes linked to deficiencies in the DNA-damage response. The role of ATM as a key regulator of signalling following DNA double-strand breaks (DSBs) has been dissected in...

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Detalles Bibliográficos
Autores principales:	Álvarez-Quilón, Alejandro, Serrano-Benítez, Almudena, Ariel Lieberman, Jenna, Quintero, Cristina, Sánchez-Gutiérrez, Daniel, Escudero, Luis M., Cortés-Ledesma, Felipe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948078/ https://www.ncbi.nlm.nih.gov/pubmed/24572510 http://dx.doi.org/10.1038/ncomms4347

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