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Early BCR Events and Antigen Capture, Processing, and Loading on MHC Class II on B Cells

B cells are efficient antigen-presenting cells (APCs), relying on antigen uptake through the B cell receptor (BCR). The mechanism of antigen recognition remains a topic of debate; while the prevalent view holds that antigens need to be multivalent for BCR activation, monovalent antigens can also ini...

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Detalles Bibliográficos
Autores principales: Avalos, Ana M., Ploegh, Hidde L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948085/
https://www.ncbi.nlm.nih.gov/pubmed/24653721
http://dx.doi.org/10.3389/fimmu.2014.00092