Screen of whole blood responses to flagellin identifies TLR5 variation associated with outcome in melioidosis

Melioidosis is a severe infection caused by the flagellated bacterium Burkholderia pseudomallei. The nonsense polymorphism TLR5(1174C>T) is associated with improved outcome in Thais with melioidosis. We hypothesized that other TLR5 variants may modulate the host response and determine outcome in...

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Detalles Bibliográficos
Autores principales: Chantratita, Narisara, Tandhavanant, Sarunporn, Myers, Nicolle D., Chierakul, Wirongrong, Robertson, Johanna D., Mahavanakul, Weera, Singhasivanon, Pratap, Emond, Mary J., Peacock, Sharon J., West, T. Eoin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948086/
https://www.ncbi.nlm.nih.gov/pubmed/24285178
http://dx.doi.org/10.1038/gene.2013.60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948086/
https://www.ncbi.nlm.nih.gov/pubmed/24285178
http://dx.doi.org/10.1038/gene.2013.60

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