An Essential Role for Medullary Thymic Epithelial Cells during the Intrathymic Development of Invariant NKT Cells

In the thymus, interactions with both cortical and medullary microenvironments regulate the development of self-tolerant conventional CD4(+) and CD8(+) αβT cells expressing a wide range of αβTCR specificities. Additionally, the cortex is also required for the development of invariant NKT (iNKT) cell...

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Detalles Bibliográficos
Autores principales: White, Andrea J., Jenkinson, William E., Cowan, Jennifer E., Parnell, Sonia M., Bacon, Andrea, Jones, Nick D., Jenkinson, Eric J., Anderson, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2014
Materias:
Immune System Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948113/
https://www.ncbi.nlm.nih.gov/pubmed/24510964
http://dx.doi.org/10.4049/jimmunol.1303057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948113/
https://www.ncbi.nlm.nih.gov/pubmed/24510964
http://dx.doi.org/10.4049/jimmunol.1303057

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