Cargando…
Clinical Pharmacology of Midazolam in Neonates and Children: Effect of Disease—A Review
Midazolam is a benzodiazepine with rapid onset of action and short duration of effect. In healthy neonates the half-life (t (1/2)) and the clearance (Cl) are 3.3-fold longer and 3.7-fold smaller, respectively, than in adults. The volume of distribution (Vd) is 1.1 L/kg both in neonates and adults. M...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948203/ https://www.ncbi.nlm.nih.gov/pubmed/24696691 http://dx.doi.org/10.1155/2014/309342 |