Structure of the SecY channel during initiation of protein translocation

Many secretory proteins are targeted by signal sequences to a protein-conducting channel, formed by prokaryotic SecY- or eukaryotic Sec61-complexes, and are translocated across the membrane during their synthesis(1,2). Crystal structures of the inactive channel show that the SecY subunit of the hete...

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Detalles Bibliográficos
Autores principales: Park, Eunyong, Ménétret, Jean-François, Gumbart, James C., Ludtke, Steven J., Li, Weikai, Whynot, Andrew, Rapoport, Tom A., Akey, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948209/
https://www.ncbi.nlm.nih.gov/pubmed/24153188
http://dx.doi.org/10.1038/nature12720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948209/
https://www.ncbi.nlm.nih.gov/pubmed/24153188
http://dx.doi.org/10.1038/nature12720

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