Resistance of LPS-activated bone marrow derived macrophages to apoptosis mediated by dexamethasone

Glucocorticoids (GC) display pleiotropic effects on the immune system. Macrophages are a major target for GC action. Here we show that dexamethasone (DEX), a synthetic GC, decreased viability of naïve bone marrow-derived macrophages (BMDM), involving an apoptotic mechanism. Administration of DEX tog...

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Detalles Bibliográficos
Autores principales: Haim, Yasmin Ohana, Unger, Naamit Deshet, Souroujon, Miriam C., Mittelman, Moshe, Neumann, Drorit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948355/
https://www.ncbi.nlm.nih.gov/pubmed/24608810
http://dx.doi.org/10.1038/srep04323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948355/
https://www.ncbi.nlm.nih.gov/pubmed/24608810
http://dx.doi.org/10.1038/srep04323

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