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Cell-SELEX Aptamer for Highly Specific Radionuclide Molecular Imaging of Glioblastoma In Vivo

Glioblastoma (GBM) is the most frequent and aggressive primary adult brain tumor with poor prognosis. Epidermal growth factor receptor variant III (EGFRvIII) is the most common and highly oncogenic EGFR mutant in GBM. With the aim to generate specific molecular probes able to target EGFRvIII with hi...

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Detalles Bibliográficos
Autores principales: Wu, Xidong, Liang, Huiyu, Tan, Yan, Yuan, Chao, Li, Shuji, Li, Xiaowen, Li, Guiping, Shi, Yusheng, Zhang, Xingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948368/
https://www.ncbi.nlm.nih.gov/pubmed/24603483
http://dx.doi.org/10.1371/journal.pone.0090752