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Solvent-Exposed Salt Bridges Influence the Kinetics of α-Helix Folding and Unfolding

[Image: see text] Salt bridges are known to play an essential role in the thermodynamic stability of the folded conformation of many proteins, but their influence on the kinetics of folding remains largely unknown. Here, we investigate the effect of Glu-Arg salt bridges on the kinetics of α-helix fo...

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Detalles Bibliográficos
Autores principales: Meuzelaar, Heleen, Tros, Martijn, Huerta-Viga, Adriana, van Dijk, Chris N., Vreede, Jocelyne, Woutersen, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948500/
https://www.ncbi.nlm.nih.gov/pubmed/24634715
http://dx.doi.org/10.1021/jz500029a