Docking, Synthesis and Antiproliferative Activity of N-Acylhydrazone Derivatives Designed as Combretastatin A4 Analogues

Cancer is the second most common cause of death in the USA. Among the known classes of anticancer agents, the microtubule-targeted antimitotic drugs are considered to be one of the most important. They are usually classified into microtubule-destabilizing (e.g., Vinca alkaloids) and microtubule-stab...

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Detalles Bibliográficos
Autores principales: do Amaral, Daniel Nascimento, Cavalcanti, Bruno C., Bezerra, Daniel P., Ferreira, Paulo Michel P., Castro, Rosane de Paula, Sabino, José Ricardo, Machado, Camila Maria Longo, Chammas, Roger, Pessoa, Claudia, Sant'Anna, Carlos M. R., Barreiro, Eliezer J., Lima, Lídia Moreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948622/
https://www.ncbi.nlm.nih.gov/pubmed/24614859
http://dx.doi.org/10.1371/journal.pone.0085380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948622/
https://www.ncbi.nlm.nih.gov/pubmed/24614859
http://dx.doi.org/10.1371/journal.pone.0085380

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