Differential Effects of Nitrostyrene Derivatives on Myelopoiesis Involve Regulation of C/EBPα and p38MAPK Activity

Bone marrow failure syndromes and MDS represent a heterogenous group of diseases, characterized by ineffective myelopoiesis, the risk of clonal evolution and a generally poor response to chemotherapy-based treatment regimen. Nitrostyrene derivatives have been studied as protein phosphatase inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales: Bartels, Marije, Calgarotto, Andrana K., Martens, Anton C., Maso, Victor, da Silva, Saulo L., Bierings, Marc B., de Souza Queiroz, Mary L., Coffer, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948686/
https://www.ncbi.nlm.nih.gov/pubmed/24614182
http://dx.doi.org/10.1371/journal.pone.0090586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948686/
https://www.ncbi.nlm.nih.gov/pubmed/24614182
http://dx.doi.org/10.1371/journal.pone.0090586

Ejemplares similares