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Differential Effects of Nitrostyrene Derivatives on Myelopoiesis Involve Regulation of C/EBPα and p38MAPK Activity
Bone marrow failure syndromes and MDS represent a heterogenous group of diseases, characterized by ineffective myelopoiesis, the risk of clonal evolution and a generally poor response to chemotherapy-based treatment regimen. Nitrostyrene derivatives have been studied as protein phosphatase inhibitor...
Autores principales: | Bartels, Marije, Calgarotto, Andrana K., Martens, Anton C., Maso, Victor, da Silva, Saulo L., Bierings, Marc B., de Souza Queiroz, Mary L., Coffer, Paul J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948686/ https://www.ncbi.nlm.nih.gov/pubmed/24614182 http://dx.doi.org/10.1371/journal.pone.0090586 |
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