The Antidepressant Agomelatine Improves Memory Deterioration and Upregulates CREB and BDNF Gene Expression Levels in Unpredictable Chronic Mild Stress (UCMS)-Exposed Mice

Agomelatine, a novel antidepressant with established clinical efficacy, acts as an agonist of melatonergic MT(1) and MT(2) receptors and as an antagonist of 5-HT(2C) receptors. The present study was undertaken to investigate whether chronic treatment with agomelatine would block unpredictable chroni...

Descripción completa

Detalles Bibliográficos
Autores principales: Gumuslu, Esen, Mutlu, Oguz, Sunnetci, Deniz, Ulak, Guner, Celikyurt, Ipek K., Cine, Naci, Akar, Furuzan, Savlı, Hakan, Erden, Faruk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948735/
https://www.ncbi.nlm.nih.gov/pubmed/24634580
http://dx.doi.org/10.4137/DTI.S13870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948735/
https://www.ncbi.nlm.nih.gov/pubmed/24634580
http://dx.doi.org/10.4137/DTI.S13870

Ejemplares similares