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Nedd4-Mediated Increase in HIV-1 Gag and Env Proteins and Immunity following DNA-Vaccination of BALB/c Mice

The late assembly domain of many viruses is critical for budding. Within these domains, encoded in viral structural proteins, are the conserved motifs PTAP, PPxY and YPxL. These sequences are the key determinants for association of viral proteins with intracellular molecules such as Tsg101, Nedd4 an...

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Detalles Bibliográficos
Autores principales: Lewis, Brad, Whitney, Stephen, Hudacik, Lauren, Galmin, Lindsey, Huaman, Maria Cecilia, Cristillo, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948788/
https://www.ncbi.nlm.nih.gov/pubmed/24614057
http://dx.doi.org/10.1371/journal.pone.0091267