CaMKII Mediates Recruitment and Activation of the Deubiquitinase CYLD at the Postsynaptic Density

NMDA treatment of cultured hippocampal neurons causes recruitment of CYLD, as well as CaMKII, to the postsynaptic density (PSD), as shown by immunoelectron microscopy. Recruitment of CYLD, a deubiquitinase specific for K63-linked polyubiquitins, is blocked by pre-treatment with tatCN21, a CaMKII inh...

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Detalles Bibliográficos
Autores principales: Thein, Soe, Tao-Cheng, Jung-Hwa, Li, Yan, Bayer, K. Ulrich, Reese, Thomas S., Dosemeci, Ayse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948843/
https://www.ncbi.nlm.nih.gov/pubmed/24614225
http://dx.doi.org/10.1371/journal.pone.0091312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948843/
https://www.ncbi.nlm.nih.gov/pubmed/24614225
http://dx.doi.org/10.1371/journal.pone.0091312

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