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Concurrent Activation of Acetylation and Tri-Methylation of H3K27 in a Subset of Hepatocellular Carcinoma with Aggressive Behavior

Analysis of acetylation and tri-methylation of the same residue of histone molecules might identify a subset of hepatocellular carcinoma (HCC) with aggressive behavior. In the present study, we examined acetylation and tri-methylation of lysine 27 on histone H3 (H3K27ac and H3K27me3, respectively) b...

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Detalles Bibliográficos
Autores principales: Hayashi, Akimasa, Yamauchi, Naoko, Shibahara, Junji, Kimura, Hiroshi, Morikawa, Teppei, Ishikawa, Shumpei, Nagae, Genta, Nishi, Akihiro, Sakamoto, Yoshihiro, Kokudo, Norihiro, Aburatani, Hiroyuki, Fukayama, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948868/
https://www.ncbi.nlm.nih.gov/pubmed/24614346
http://dx.doi.org/10.1371/journal.pone.0091330