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E2 Proteins of High Risk Human Papillomaviruses Down-Modulate STING and IFN-κ Transcription in Keratinocytes

In the early stages of human papillomavirus (HPV) infection, the viral proteins elicit specific immune responses that can participate to regression of ano-genital lesions. HPV E6 protein for instance can reduce type I interferon (IFN) including IFN-κ that is involved in immune evasion and HPV persis...

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Detalles Bibliográficos
Autores principales: Sunthamala, Nuchsupha, Thierry, Francoise, Teissier, Sebastien, Pientong, Chamsai, Kongyingyoes, Bunkerd, Tangsiriwatthana, Thumwadee, Sangkomkamhang, Ussanee, Ekalaksananan, Tipaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948877/
https://www.ncbi.nlm.nih.gov/pubmed/24614210
http://dx.doi.org/10.1371/journal.pone.0091473