Incidence of Infection in Prnp ARR/ARR Sheep following Experimental Inoculation with or Natural Exposure to Classical Scrapie

The prion protein gene (Prnp) is highly influential in determining risk and susceptibility of sheep exposed to classical scrapie. Sheep homozygous for alanine at codon 136 and arginine at codons 154 and 171 (ARR/ARR) of the Prnp gene are historically considered to be highly resistant to classical sc...

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Detalles Bibliográficos
Autores principales: Jeffrey, Martin, Martin, Stuart, Chianini, Francesca, Eaton, Samantha, Dagleish, Mark P., González, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948952/
https://www.ncbi.nlm.nih.gov/pubmed/24614120
http://dx.doi.org/10.1371/journal.pone.0091026