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Incidence of Infection in Prnp ARR/ARR Sheep following Experimental Inoculation with or Natural Exposure to Classical Scrapie
The prion protein gene (Prnp) is highly influential in determining risk and susceptibility of sheep exposed to classical scrapie. Sheep homozygous for alanine at codon 136 and arginine at codons 154 and 171 (ARR/ARR) of the Prnp gene are historically considered to be highly resistant to classical sc...
Autores principales: | Jeffrey, Martin, Martin, Stuart, Chianini, Francesca, Eaton, Samantha, Dagleish, Mark P., González, Lorenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948952/ https://www.ncbi.nlm.nih.gov/pubmed/24614120 http://dx.doi.org/10.1371/journal.pone.0091026 |
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