Cargando…

Ubiquitination Events That Regulate Recombination of Immunoglobulin Loci Gene Segments

Programed DNA mutagenesis events in the immunoglobulin (Ig) loci of developing B cells utilize the common and conserved mechanism of protein ubiquitination for subsequent proteasomal degradation to generate the required antigen-receptor diversity. Recombinase proteins RAG1 and RAG2, necessary for V(...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chao, Jaime, Rothschild, Gerson, Basu, Uttiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949197/ https://www.ncbi.nlm.nih.gov/pubmed/24653725 http://dx.doi.org/10.3389/fimmu.2014.00100

Ejemplares similares

Expression and Function of Tetraspanins and Their Interacting Partners in B Cells
por: Zou, Fagui, et al.
Publicado: (2018)

Organization and Complexity of the Yak (Bos Grunniens) Immunoglobulin Loci
por: Wu, Mingli, et al.
Publicado: (2022)

Characterization of immunoglobulin loci in the gigantic genome of Ambystoma mexicanum
por: Martinez-Barnetche, Jesús, et al.
Publicado: (2023)

Transcriptional stalling in B-lymphocytes: A mechanism for antibody diversification and maintenance of genomic integrity
por: Sun, Jianbo, et al.
Publicado: (2013)

Gene prediction in the immunoglobulin loci
por: Sirupurapu, Vikram, et al.
Publicado: (2022)

Structure and Diversity of the Rhesus Macaque Immunoglobulin Loci through Multiple De Novo Genome Assemblies
por: Ramesh, Akshaya, et al.
Publicado: (2017)

De novo Inference of Diversity Genes and Analysis of Non-canonical V(DD)J Recombination in Immunoglobulins
por: Safonova, Yana, et al.
Publicado: (2019)

AIDing Chromatin and Transcription-Coupled Orchestration of Immunoglobulin Class-Switch Recombination
por: Vaidyanathan, Bharat, et al.
Publicado: (2014)

On the Dark Side of Therapies with Immunoglobulin Concentrates: The Adverse Events
por: Späth, Peter J., et al.
Publicado: (2015)

CTCF and ncRNA Regulate the Three-Dimensional Structure of Antigen Receptor Loci to Facilitate V(D)J Recombination
por: Choi, Nancy M., et al.
Publicado: (2014)

Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination
por: Rogers, Carolyn H., et al.
Publicado: (2021)

RAG1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci
por: Hewitt, Susannah L., et al.
Publicado: (2009)

Clonal Progression during the T Cell-Dependent B Cell Antibody Response Depends on the Immunoglobulin D(H) Gene Segment Repertoire
por: Trad, Ahmad, et al.
Publicado: (2014)

Expression of Constitutive Fusion of Ubiquitin to PCNA Restores the Level of Immunoglobulin A/T Mutations During Somatic Hypermutation in the Ramos Cell Line
por: Lerner, Leticia K., et al.
Publicado: (2022)

Unveiling the Diversity of Immunoglobulin Heavy Constant Gamma (IGHG) Gene Segments in Brazilian Populations Reveals 28 Novel Alleles and Evidence of Gene Conversion and Natural Selection
por: Calonga-Solís, Verónica, et al.
Publicado: (2019)

Recombinant Human C1 Esterase Inhibitor for the Management of Adverse Events Related to Intravenous Immunoglobulin Infusion in Patients With Common Variable Immunodeficiency or Polyneuropathy: A Pilot Open-Label Study
por: Melamed, Isaac R., et al.
Publicado: (2021)

Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci
por: Loguercio, Salvatore, et al.
Publicado: (2018)

Regulation of Fc Receptor Endocytic Trafficking by Ubiquitination
por: Molfetta, Rosa, et al.
Publicado: (2014)

Switch Tandem Repeats Influence the Choice of the Alternative End-Joining Pathway in Immunoglobulin Class Switch Recombination
por: Oudinet, Chloé, et al.
Publicado: (2022)

Factors important in evolutionary shaping of immunoglobulin gene loci
por: Barak, Michal, et al.
Publicado: (2010)

Effects of senataxin and RNA exosome on B-cell chromosomal integrity
por: Kazadi, David, et al.
Publicado: (2020)

The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3
por: Tang, Tiantian, et al.
Publicado: (2021)

Chicken MBD4 Regulates Immunoglobulin Diversification by Somatic Hypermutation
por: Costello, Ryan, et al.
Publicado: (2019)

Regulation of MHC Class II-Peptide Complex Expression by Ubiquitination
por: Cho, Kyung-Jin, et al.
Publicado: (2013)

Roles of Ubiquitination and Deubiquitination in Regulating Dendritic Cell Maturation and Function
por: Zhu, Bo, et al.
Publicado: (2020)

Immunoglobulin and T Cell Receptor Genes: IMGT(®) and the Birth and Rise of Immunoinformatics
por: Lefranc, Marie-Paule
Publicado: (2014)

A Proposed New Nomenclature for the Immunoglobulin Genes of Mus musculus
por: Busse, Christian E., et al.
Publicado: (2019)

Comparative Aspects of Immunoglobulin Gene Rearrangement Arrays in Different Species
por: Sinkora, Marek, et al.
Publicado: (2022)

Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination
por: Matheson, Louise S., et al.
Publicado: (2017)

Editorial: Ubiquitin and ubiquitin-like modifications in viral infection and innate immunity
por: Sparrer, Konstantin M. J., et al.
Publicado: (2023)

Functional Versatility of AGY Serine Codons in Immunoglobulin Variable Region Genes
por: Detanico, Thiago, et al.
Publicado: (2016)

Identification of a Shrimp E3 Ubiquitin Ligase TRIM50-Like Involved in Restricting White Spot Syndrome Virus Proliferation by Its Mediated Autophagy and Ubiquitination
por: Zhao, Chao, et al.
Publicado: (2021)

Analyzing Immunoglobulin Repertoires
por: Chaudhary, Neha, et al.
Publicado: (2018)

Discovery of a Recombinant Human Monoclonal Immunoglobulin G Antibody Against α-Latrotoxin From the Mediterranean Black Widow Spider (Latrodectus tredecimguttatus)
por: Føns, Sofie, et al.
Publicado: (2020)

Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities
por: Russell, Magdalena L, et al.
Publicado: (2022)

Immunoglobulin Gene Repertoire Diversification and Selection in the Stomach – From Gastritis to Gastric Lymphomas
por: Michaeli, Miri, et al.
Publicado: (2014)

Epigenetic Regulation of Individual Modules of the immunoglobulin heavy chain locus 3′ Regulatory Region
por: Birshtein, Barbara K.
Publicado: (2014)

Human Dendritic Cells Express the Complement Receptor Immunoglobulin Which Regulates T Cell Responses
por: Munawara, Usma, et al.
Publicado: (2019)

Blood-Borne ST6GAL1 Regulates Immunoglobulin Production in B Cells
por: Irons, Eric E., et al.
Publicado: (2020)

Regulation of Lymphatic GM-CSF Expression by the E3 Ubiquitin Ligase Cbl-b
por: Peer, Sebastian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dhdabb6go0n27umn8pj2j8s3ru