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In silico study of ligand binding site of toll-like receptor 5

BACKGROUND: Toll-like receptor-5 (TLR-5) is a member of TLRs family and responsible for bacterial flagellin recognition. The activation of TLR-5 with flagellin leads to initiation of signaling cascades, which in turn results in transcription of pro-inflammatory cytokines. Regarding the critical role...

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Detalles Bibliográficos
Autores principales: Savar, Nastaran Sadat, Bouzari, Saeid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949343/
https://www.ncbi.nlm.nih.gov/pubmed/24627849
http://dx.doi.org/10.4103/2277-9175.125730