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The effect of iron availability on transcription of the Neisseria meningitidis fHbp gene varies among clonal complexes

Factor H binding protein (fHbp) is a major antigenic component of novel vaccines designed to protect against meningococcal disease. Prediction of the potential coverage of these vaccines is difficult, as fHbp is antigenically variable and levels of expression differ among isolates. Transcriptional r...

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Detalles Bibliográficos
Autores principales: Sanders, Holly, Brehony, Carina, Maiden, Martin C. J., Vipond, Caroline, Feavers, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949423/
https://www.ncbi.nlm.nih.gov/pubmed/22241045
http://dx.doi.org/10.1099/mic.0.054957-0