Cargando…

Population pharmacokinetics of olprinone in healthy male volunteers

BACKGROUND: Olprinone decreases the cardiac preload and/or afterload because of its vasodilatory effect and increases myocardial contractility by inhibiting phosphodiesterase III. PURPOSE: The objective of this study was to characterize the population pharmacokinetics of olprinone after a single con...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunisawa, Takayuki, Kasai, Hidefumi, Suda, Makoto, Yoshimura, Manabu, Sugawara, Ami, Izumi, Yuki, Iida, Takafumi, Kurosawa, Atsushi, Iwasaki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949558/
https://www.ncbi.nlm.nih.gov/pubmed/24623995
http://dx.doi.org/10.2147/CPAA.S50626