Neuronal activity regulates extracellular tau in vivo

Tau is primarily a cytoplasmic protein that stabilizes microtubules. However, it is also found in the extracellular space of the brain at appreciable concentrations. Although its presence there may be relevant to the intercellular spread of tau pathology, the cellular mechanisms regulating tau relea...

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Detalles Bibliográficos
Autores principales: Yamada, Kaoru, Holth, Jerrah K., Liao, Fan, Stewart, Floy R., Mahan, Thomas E., Jiang, Hong, Cirrito, John R., Patel, Tirth K., Hochgräfe, Katja, Mandelkow, Eva-Maria, Holtzman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949564/
https://www.ncbi.nlm.nih.gov/pubmed/24534188
http://dx.doi.org/10.1084/jem.20131685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949564/
https://www.ncbi.nlm.nih.gov/pubmed/24534188
http://dx.doi.org/10.1084/jem.20131685

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