Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice

The preferential localization of some neoplasms, such as serrated polyps (SPs), in specific areas of the intestine suggests that nongenetic factors may be important for their development. To test this hypothesis, we took advantage of transgenic mice that expressed HB-EGF throughout the intestine but...

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Detalles Bibliográficos
Autores principales: Bongers, Gerold, Pacer, Michelle E., Geraldino, Thais H., Chen, Lili, He, Zhengxiang, Hashimoto, Daigo, Furtado, Glaucia C., Ochando, Jordi, Kelley, Kevin A., Clemente, Jose C., Merad, Miriam, van Bakel, Harm, Lira, Sergio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949565/
https://www.ncbi.nlm.nih.gov/pubmed/24590763
http://dx.doi.org/10.1084/jem.20131587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949565/
https://www.ncbi.nlm.nih.gov/pubmed/24590763
http://dx.doi.org/10.1084/jem.20131587

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