Consequences of the recurrent MYD88(L265P) somatic mutation for B cell tolerance

MYD88(L265P) has recently been discovered as an extraordinarily frequent somatic mutation in benign monoclonal IgM gammopathy, Waldenström’s macroglobulinemia, and diffuse large B cell lymphoma. In this study, we analyze the consequences for antigen-activated primary B cells of acquiring MYD88(L265P...

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Detalles Bibliográficos
Autores principales: Wang, James Q., Jeelall, Yogesh S., Beutler, Bruce, Horikawa, Keisuke, Goodnow, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949567/
https://www.ncbi.nlm.nih.gov/pubmed/24534189
http://dx.doi.org/10.1084/jem.20131424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949567/
https://www.ncbi.nlm.nih.gov/pubmed/24534189
http://dx.doi.org/10.1084/jem.20131424

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