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Consequences of the recurrent MYD88(L265P) somatic mutation for B cell tolerance

MYD88(L265P) has recently been discovered as an extraordinarily frequent somatic mutation in benign monoclonal IgM gammopathy, Waldenström’s macroglobulinemia, and diffuse large B cell lymphoma. In this study, we analyze the consequences for antigen-activated primary B cells of acquiring MYD88(L265P...

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Detalles Bibliográficos
Autores principales:	Wang, James Q., Jeelall, Yogesh S., Beutler, Bruce, Horikawa, Keisuke, Goodnow, Christopher C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949567/ https://www.ncbi.nlm.nih.gov/pubmed/24534189 http://dx.doi.org/10.1084/jem.20131424

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