The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity

Tyrosine phosphorylation of signaling molecules that mediate B cell activation in response to various stimuli is tightly regulated by protein tyrosine phosphatases (PTPs). PTP1B is a ubiquitously expressed tyrosine phosphatase with well-characterized functions in metabolic signaling pathways. We sho...

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Detalles Bibliográficos
Autores principales: Medgyesi, David, Hobeika, Elias, Biesen, Robert, Kollert, Florian, Taddeo, Adriano, Voll, Reinhard E., Hiepe, Falk, Reth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949573/
https://www.ncbi.nlm.nih.gov/pubmed/24590766
http://dx.doi.org/10.1084/jem.20131196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949573/
https://www.ncbi.nlm.nih.gov/pubmed/24590766
http://dx.doi.org/10.1084/jem.20131196

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