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Genetic Polymorphism rs6922269 in the MTHFD1L Gene Is Associated with Survival and Baseline Active Vitamin B12 Levels in Post-Acute Coronary Syndromes Patients

BACKGROUND AND AIMS: The methylene-tetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L) gene is involved in mitochondrial tetrahydrofolate metabolism. Polymorphisms in MTHFD1L, including rs6922269, have been implicated in risk for coronary artery disease (CAD). We investigated the assoc...

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Detalles Bibliográficos
Autores principales: Palmer, Barry R., Slow, Sandy, Ellis, Katrina L., Pilbrow, Anna P., Skelton, Lorraine, Frampton, Chris M., Palmer, Suetonia C., Troughton, Richard W., Yandle, Tim G., Doughty, Rob N., Whalley, Gillian A., Lever, Michael, George, Peter M., Chambers, Stephen T., Ellis, Chris, Richards, A. Mark, Cameron, Vicky A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949666/
https://www.ncbi.nlm.nih.gov/pubmed/24618918
http://dx.doi.org/10.1371/journal.pone.0089029